Endometrial Receptivity Array (ERA)
Caring for Every Stage of Womanhood
Endometrial Receptivity Array (ERA) Test – Discover the Perfect Time for Embryo Transfer
What is the Endometrial Receptivity Array (ERA)?
How the ERA Test Works
The ERA test is a cutting-edge molecular diagnostic procedure performed in a few key steps:
Endometrial Biopsy: A small tissue sample is collected from the uterine lining, usually after 5 days of progesterone exposure in a mock or natural cycle.
Genetic Analysis: The sample undergoes next-generation sequencing (NGS) to examine the activity of more than 200 genes involved in endometrial receptivity.
Personalized Report: Results reveal whether the endometrium is receptive or non-receptive on the day of the biopsy.
Customized Timing: If non-receptive, the report recommends an adjusted embryo transfer window (earlier or later) for future IVF cycles.
Benefits of Endometrial Receptivity Array Testing
The ERA test provides several key advantages:
Personalized Embryo Transfer: Identifies the exact day and hour when the uterus is most receptive.
Improved IVF Success: Studies show higher implantation and pregnancy rates in patients with previous IVF failures.
Reduces Repeated IVF Attempts: Saves emotional stress, time, and cost by avoiding transfers at the wrong time.
Evidence-Based Approach: Backed by extensive clinical research and advanced genomic science.
Who Should Consider an ERA Test?
ERA testing is recommended for:
Couples experiencing recurrent implantation failure despite transferring high-quality embryos.
Women with unexplained infertility or repeated early miscarriages.
Patients with normal embryo quality but multiple failed IVF cycles.
Women with thin or irregular endometrium who need precise timing.
The Science Behind Endometrial Receptivity
Implantation is a delicate process that depends on a synchronized interaction between a healthy embryo and a receptive uterine lining.
The window of implantation usually occurs around Day 19–21 of a natural cycle, but it can vary by 12–48 hours among individuals.
ERA testing measures gene expression to identify whether the endometrium is pre-receptive, receptive, or post-receptive.
By tailoring the embryo transfer to the exact window, the chances of successful implantation are greatly improved.
ERA Test Procedure at Avni Hospital
At Avni Hospital, the ERA test is performed in a comfortable and safe environment:
Cycle Preparation: The patient undergoes either a mock cycle or natural cycle monitoring.
Endometrial Sampling: A painless, outpatient biopsy is performed using a thin catheter.
Laboratory Analysis: The tissue sample is shipped to a specialized genetic lab for RNA sequencing.
Personalized Transfer Plan: Our fertility specialists interpret the results to schedule the optimal embryo transfer.
ERA Test and IVF Success Rates
Research shows that 25% of women with recurrent IVF failure have a displaced implantation window.
Adjusting embryo transfer timing based on ERA results can improve implantation rates by up to 20–30%.
Couples with a history of failed IVF cycles often experience higher clinical pregnancy rates when using ERA-guided transfer.
Safety and Accuracy
Minimally Invasive: The biopsy is a simple office procedure with minimal discomfort.
High Accuracy: ERA uses next-generation sequencing to provide a 99% reproducibility rate.
No Impact on Fertility: The test does not damage the uterus or affect future implantation.
Preparing for the ERA Test
To ensure reliable results:
Follow your fertility specialist’s instructions on cycle monitoring and progesterone intake.
Avoid sexual intercourse or vaginal medications before the biopsy as advised.
Inform your doctor about any infections or bleeding disorders.
Why Choose Avni Hospital for ERA Testing
At Avni Your Hospital, we combine cutting-edge technology with compassionate care:
Advanced Laboratory Support: We partner with leading genetic labs for precise ERA analysis.
Expert Fertility Specialists: Our team tailors embryo transfer timing based on ERA findings for the best possible outcomes.
Integrated IVF Services: From ovarian stimulation to embryo transfer, every step is seamlessly managed under one roof.
Proven Track Record: High pregnancy rates in patients with previous failed cycles.
FAQs About Endometrial Receptivity Array (ERA)
The biopsy may cause mild cramping, but it is generally well tolerated.
Typically during a mock cycle, after 5 days of progesterone supplementation.
Reports are usually available within 10–15 days.
While it cannot guarantee pregnancy, ERA significantly increases the chance of successful implantation when used with high-quality embryos.
Send us a message
+91 9856463333
Kompally , secunderabad
